The meaning at work through impact on individual and work goals has a significant impact on the relationship between different variables in work environments. This research was conducted with the aim of determining the moderating role of meaning at work on the relationship between self-leadership with affective capital and affective-collective investment. Research statistical population was the employees of Saderat bank in Isfahan city. Among them, 243 employees were selected using convenience sampling. Research instruments were self-leadership questionnaire (Houghton et al, 2012), meaning at work questionnaire (Steger et al, 2012), affective capital questionnaire (Golparvar, 2017) and affective-collective investment questionnaire (Golparvar, 2018). Data were analyzed with the use of Pearson correlation coefficient and hierarchical regression analysis. Results revealed that there is positive significant relationship between self-leadership with meaning at work, affective capital and affective-collective investment. Results of hierarchical regression analysis indicated that meaning at work moderates the relationship between self-leadership with affective capital and affective-collective investment. This means that when meaning at work is high, there is a positive significant relationship between self-leadership with affective capital and affective-collective investment (p<0.01), but when meaning at work is low, there is not a significant relationship between self-leadership with affective capital and affective-collective investment (p¬>0.05). The results show that meaning at work have high power to impact the relationship between self-leadership with affective capital and affective-collective investment
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